Method for analyzing a patient's genetic prediposition to at least one disease and amplification adapted to such a method

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United States of America Patent

PATENT NO 7060438
SERIAL NO

09979088

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A patient's genetic predisposition to a disease may be analyzed by placing, in the presence of probes, at least one type of amplicon, derived from the amplification of at least one polymorphic region of nucleic acid from the patient. The polymorphic region is a polymorphic region of interest with respect to the disease(s) being sought. The probes include at least one specific 'low-resolution' typing probe that has the ability to hybridize to the polymorphic region of interest of at least one gene or a group of alleles of this gene carried by the amplicon and associated with the disease(s); and at least one specific 'high-resolution' subtyping probe that has the ability to hybridize to the polymorphic region of interest of the allele or of the group of alleles specific for the 'low-resolution' typing probe, the high-resolution probe(s) making it possible to distinguish the allele(s) associated with susceptibility and/or the allele(s) associated with resistance to the disease(s), according to whether or not they hybridize.

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Patent Owner(s)

Patent OwnerAddress
BIO MERIEUX69280 MARCY L'ETOILE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Mougin, Bruno Lyons, FR 15 39
Tiercy, Jean-Marie Chenes bou Geries, CH 2 11

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