Methods for inducing HIV-neutralizing antibodies
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United States of America Patent
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Jun 6, 2006
Grant Date -
Jan 15, 2004
app pub date -
May 15, 2003
filing date -
May 17, 2002
priority date (Note) -
Expired
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Abstract
The present invention relates to a method for inducing antibodies neutralizing HIV primary isolates in a mammal, comprising administration of a pharmaceutical composition comprising a polypeptide represented by the formula N-L-C, in which: N represents the amino acid sequence 25 81 of gp41, C represents the amino acid sequence 112 157 of gp41, and L represents a flexible linking sequence comprising from 2 to 30 amino acids.
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