Rationally designed heparinases derived from heparinase I and II

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United States of America Patent

PATENT NO 7056504
SERIAL NO

09384959

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Abstract

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Modified heparinases having altered binding specificity and activity are provided. Isolated nucleic acids encoding the same as well as vectors and host cells are provided. Methods for using the modified heparinases are also provided.

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Patent Owner(s)

  • MASSACHUSETTS INSTITUTE OF TECHNOLOGY;MEDI-GLOBE VERTRIEBS - GMBH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Liu, Dongfang Framingham, MA 31 667
Sasisekharan, Ram Cambridge, MA 136 3562
Shriver, Zachary Cambridge, MA 116 1834
Venkataraman, Ganesh Woburn, MA 97 2138

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