Bifunctional chelating agent for actinium
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United States of America Patent
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May 16, 2006
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app pub date -
Sep 13, 2002
filing date -
Sep 17, 2001
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Abstract
The invention concerns a ligand comprising (I) wherein n is an integer from 1 to 5 Y is CO2H or PO3H2T represents --X or -phenyl-X, wherein X represents NO2, NH2, NCS, NHCOCH2-Z, NHCO--W--COCNHS, --NH-Q, --NHCS-Q, --NHCOCH2-Q, or NHCO(CH2)m-Q where Q is a hapten chosen from the group consisting of steroids, enzymes, proteins, monoclonal antibodies, chimeric antibodies, or fragments thereof or any activated linker ready for coupling reaction, W is --(CH2)m- m is an integer from 1 to 10 Z is chloride, bromide or iodine ##STR00001##
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