.beta.-lactam compounds process for reproducing the same and serum cholesterol-lowering agents containing the same
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
May 16, 2006
Grant Date -
Apr 1, 2004
app pub date -
Feb 20, 2002
filing date -
Feb 23, 2001
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
Novel .beta.-lactam compounds represented by the following formula (I) or pharmaceutically acceptable salts thereof which are useful as serum cholesterol-lowering agents: ##STR00001## (I) wherein A.sub.1, A.sub.3 and A.sub.4 represent each hydrogen, halogen C.sub.1-5 alkyl, C.sub.1-5 alkoxy, --COOR.sub.1, a group represented by the following general formula (b): (b) wherein R.sub.1 represents hydrogen or C.sub.1-5 alkyl, or a group represented by the following general formula (a): (a) wherein R.sub.2 represents --CH.sub.2OH, --CH.sub.2OC(O)--R.sub.1 or --CO.sub.2--R.sub.1; R.sub.3 represents --OH or --OC(O)--R.sub.1; R.sub.4 represents --(CH.sub.2).sub.kR.sub.5(CH.sub.2).sub.1- wherein K and 1 are each 0 or an integer of 1 or above provided k+1 is an integer of not more than 10; and R.sub.5 represents a single bond, --CH.dbd.CH--, --OCH.sub.2--, carbonyl or --CH(OH)--; provided that at least one of A.sub.1, A.sub.3 and A.sub.4 is a group represented by the above formula (a); A.sub.2 represents C.sub.1-5 alkyl, C.sub.1-5 alkoxy, C.sub.1-5 alkenyl, C.sub.1-5 hydroxyalkyl or C.sub.1-5 carbonylalkyl; and n, p, q and r are each an integer of 0, 1 or 2.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully