Helper dependent adenovirus vectors based on integrase family site-specific recombinases
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United States of America Patent
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May 16, 2006
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Jul 26, 2002
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Jun 24, 1993
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Abstract
This invention provides helper-dependent adenovirus cloning vectors and helper adenoviruses, and methods for making and Using such preparations, wherein the helper adenoviruses contain recombinase target sites that are useful in reducing the level of contamination of helper virus in helper-dependent adenovirus vector preparations.
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