Anti-dioxins monoclonal antibody suitable for assaying dioxins in environment and hybridoma producing the same
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United States of America Patent
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May 2, 2006
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app pub date -
Jul 7, 2004
filing date -
Jan 8, 2004
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Abstract
The object of present invention is to provide an immunoassay for dioxins which can rapidly and simply afford measured values having a good correlation with analytical values of dioxins by the official method (GC/MS method). The above object is achieved by using the monoclonal antibody of the present invention having not only a reactivity with the indicator isomer among 17 kinds of PCDDs and PCDFs each having a predetermined WHO-TEF value, but also a high cross-reactivity with several kinds of dioxin isomers having five or six chlorine atoms which contribute largely to a TEQ value, and also having a stable reactivity with the antigens in a measuring solvent.
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