Immunostimulant compositions comprising an aminoalkyl glucosaminide phosphate and QS-21
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United States of America Patent
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Apr 18, 2006
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N/A
app pub date -
Jun 21, 2002
filing date -
Feb 4, 2002
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Abstract
The invention provides pharmaceutical compositions, particularly vaccine compositions, employing an adjuvant system comprising RC-529 (an aminoalkyl glucosaminide phosphate compound) and QS-21 (a saponin). Such compositions synergistically enhance the immune response in a mammal to a co-administered antigen. Also provided are methods of using the compositions in the treatment of various human diseases, including cancer, microbial infections and autoimmune disorders.
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