Interaction between cyclin D1 and steroid receptor co-activators and uses thereof in assays
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Mar 14, 2006
Issued Date -
N/A
app pub date -
Sep 14, 2001
filing date -
Feb 12, 1998
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
The present invention relates to the finding that cyclin D1 interacts in a ligand-independent fashion with coactivators of the SRC-1 family. The direct interaction of cyclin D1 enhances estrogen receptor (ER) mediated transcription and provides a novel target for the development of assays for substances which modulate the cell cycle. The invention provides assay methods for the prevention of growth of tumors, for assays for compounds useful in the prevention of tumors and compounds obtainable by such assays.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully