Tetrapeptide derivative TZT-1027 crystal
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United States of America Patent
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Mar 7, 2006
Grant Date -
Dec 16, 2004
app pub date -
Sep 19, 2002
filing date -
Sep 20, 2001
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Abstract
The invention provides crystals of N2-(N,N-dimethyl-L-valyl)-N-[(1S,2R)-2-methoxy-4-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[(2-phenylethyl)amino]propyl]-1-pyrrolidinyl]-1-[(S)-1-methylpropyl]-4-oxobutyl]-N-methyl-L-valinamide or salts thereof which possess potent antitumor activity and methods for their preparation.
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