Oncolytic adenovirus
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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Feb 21, 2006
Issued Date -
N/A
app pub date -
Nov 14, 2000
filing date -
Nov 15, 1999
priority date (Note) -
Expired
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Abstract
Viral vectors and methods of making such vectors are described that preferentially kill neoplastic but not normal cells, the preferred vector being an adenovirus that has the endogenous promoters in the E1A and/or E4 regions substituted with a tumor specific promoter which is preferably E2F responsive.
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