Method for screening using an OAT1 transporter protein
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United States of America Patent
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Jan 17, 2006
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N/A
app pub date -
May 18, 1998
filing date -
May 23, 1997
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Abstract
A protein capable of transporting organic anions having amino acid sequences represented by SEQ ID NO: 1 or 2 or amino acid sequences derived therefrom by deletion, substitution or addition of one or more amino acid residues; and a gene coding for the protein. The protein and gene therefore are useful in vitro analysis of drug release and drug—drug interactions and development of method for screening drugs useful for preventing nephrotoxicity.
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