Ocular analyte sensor
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United States of America Patent
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Dec 27, 2005
Grant Date -
Mar 6, 2003
app pub date -
Oct 11, 2002
filing date -
Aug 26, 1999
priority date (Note) -
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status (Latency Note)
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Abstract
An ophthalmic lens comprising a receptor moiety can be used to determine the amount of an analyte in an ocular fluid. The receptor moiety can bind either a specific analyte or a detectably labeled competitor moiety. The amount of detectably labeled competitor moiety which is displaced from the receptor moiety by the analyte is measured and provides a means of determining analyte concentration in an ocular fluid, such as tears, aqueous humor, or interstitial fluid. The concentration of the analyte in the ocular fluid, in turn, indicates the concentration of the analyte in a fluid or tissue sample of the body, such as blood or intracellular fluid.
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