Carboxylic acid derivatives that inhibit the binding of integrins to their receptors

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United States of America Patent

PATENT NO 6972296
APP PUB NO 20040063955A1
SERIAL NO

09973142

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method for the inhibition of the binding of α4β1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and to the use of such compounds either a above, or in formulations for the control or prevention of diseases states in which α4β1 is involved.

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Patent Owner(s)

Patent OwnerAddress
ENCYSIVE PHARMACEUTICALS INC6700 WEST LOOP SOUTH 4TH FLOOR BELLAIRE TX 77401

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Biediger, Ronald J Houston, TX 27 342
Chen, Qi Carmel, IN 279 1873
Decker, E Radford Houston, TX 3 145
Holland, George W Houston, TX 41 410
Kassir, Jamal M Stafford, TX 5 203
Li, Jian The Woodlands, TX 590 16324
Li, Wen Pearland, TX 360 5286
Market, Robert V Pearland, TX 21 254
Scott, Ian L Delanson, NY 47 756
Wu, Chengde Pearland, TX 81 1161

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