Method of purification of molecules using unbranched terminal alkyldiols
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United States of America Patent
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Nov 22, 2005
Grant Date -
Dec 5, 2002
app pub date -
Mar 19, 2001
filing date -
Mar 19, 2001
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Abstract
The current invention provides methods for molecule purification by RP-LC and RP-HPLC that uses unbranched terminal alkyldiols as eluting solvents. In particular, the present invention purifies molecules, particularly proteins and peptides, on reverse phase liquid chromatography columns using a buffer containing either 1,5 pentanediol, 1,6 hexanediol or 1,7 heptanediol.
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