Methods for detecting nucleic acids indicative of cancer
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United States of America Patent
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Nov 15, 2005
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N/A
app pub date -
Apr 7, 2000
filing date -
Apr 9, 1999
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Abstract
The invention provides methods for screening tissue or body fluid samples for nucleic acid indicia of cancer or precancer. Method are provided for screening a patient for cancer or precancer by detecting the presence of nucleic acid fragments that are longer than nucleic acid fragments expected to be present in a sample obtained from a healthy individual. In one embodiment, a positive screen for cancer or precancer is identified when a patient tissue or body fluid sample comprising exfoliated cells or cellular debris contains an amount of nucleic acid of a length greater than about 200 base pairs that exceeds a predetermined amount.
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