Expression of recombinant human proteins in Tetrahymena
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United States of America Patent
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Nov 8, 2005
Grant Date -
Nov 27, 2003
app pub date -
Mar 24, 2003
filing date -
Mar 30, 2002
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Abstract
The present invention concerns a method for production of recombinant human proteins, in which Tetrahymena cells are transformed with recombinant DNA containing at least one functional gene that codes for a human protein, the recombinant Tetrahymena cells are cultured, in which the gene that codes for a human protein is expressed and the proteins are then isolated. The present invention also concerns a corresponding method, in which the gene that codes for a human protein contains a human leader sequence that leads to secretion of the expressed protein.
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