Spontaneous emulsions containing cyclosporine
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United States of America Patent
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Nov 1, 2005
Grant Date -
Mar 13, 2003
app pub date -
Aug 31, 2001
filing date -
Aug 31, 2001
priority date (Note) -
Expired
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Abstract
A pharmaceutical composition contains cyclosporine as the active ingredient. More specifically, the composition is an orally administered pharmaceutical formulation in the form of a spontaneous emulsion comprising cyclosporine, ethanol ethyl oleate and polyoxyethylene glycerol trioleate. A method for preparing an orally administered pharmaceutical composition involves first dissolving cyclosporine in ethanol. Polyoxyethylene glycerol trioleate and an oil component are then added, mixed and diluted in an aqueous media to form a spontaneous emulsion.
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