Recombinant bacterial cells for delivery of PNP to tumor cells

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United States of America Patent

PATENT NO 6958318
SERIAL NO

10198034

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Abstract

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The present invention provides a procaryotic host cell stably transformed or transfected by a vector including a DNA sequence encoding for purine nucleoside phosphorylase or hydrolase. The transformed or transfected procaryotic host cell can be used in combination with a purine substrate to treat tumor cells and/or virally infected cells.

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Patent Owner(s)

Patent OwnerAddress
THE UAB RESEARCH FOUNDATION1530 3RD AVENUE SOUTH AB 770 BIRMINGHAM AL 35294-0107
SOUTHERN RESEARCH INSTITUTEOFFICE OF COMMERCIALIZATION AND INTELL PROP 2000 9TH AVE SOUTH PO BOX 55305 BIRMINGHAM AL 35205-5305

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bennett, Jr Leonard L Birmingham, AL 4 99
Gadi, Vijayakrishna K Birmingham, AL 8 58
Parker, William B Birmingham, AL 24 350
Sorscher, Eric J Birmingham, AL 22 156
Waud, William Mountain Brook, AL 3 49

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