Inhibition of tau-tau association
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United States of America Patent
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Oct 11, 2005
Grant Date -
Nov 14, 2002
app pub date -
Mar 28, 2002
filing date -
Mar 27, 1995
priority date (Note) -
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Abstract
A composition and use thereof for the prophylaxis or treatment of Alzheimer's disease, motor neurone disease, Lewy body disease, Pick's disease or progressive supranuclear palsy. The composition includes an agent which modulates or inhibits tau-tau association and which does not inhibit tau-tubulin binding. In the method the agent is administered to an individual in order to achieve the desired therapeutic effect. Preferably the agent which is administered is a phenothiazine compound.
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