Pro-micelle pharmaceutical compositions
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United States of America Patent
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Oct 4, 2005
Grant Date -
Apr 24, 2003
app pub date -
Oct 11, 2001
filing date -
Oct 11, 2001
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention provides pro-micelle compositions comprising a pharmaceutically active agent encapsulated with a membrane of esterified C12-C18 fatty acids. In the mammalian intestine, exposure to C12-C18 fatty acids results in conversion of the pro-micelle to a stable micelle that effectively delivers the pharmaceutically active agent to the systemic circulation. The present invention further provides methods of making and using such compositions.
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