Polyglycerol and lactose compositions for the protection of living systems from states of reduced metabolism
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United States of America Patent
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Sep 27, 2005
Grant Date -
Feb 6, 2003
app pub date -
Feb 1, 2002
filing date -
Nov 30, 1999
priority date (Note) -
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Abstract
Polyglycerol, lactose, and a combination of polyglycerol and lactose are effective at preserving cells, tissues, and organs from damage due to hypothermic, ischemic, or other metabolic impairment, and a mixture of polyglycerol plus lactose is particularly useful for the hypothermic storage of cells, tissues, and organs. The mixture of polyglycerol and lactose can be further improved by the addition of chondroitin sulfate, chlorpromazine, calcium, citrate, glutathione, adenine, glucose, magnesium, and a pH buffer.
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