Multiplexed analysis of clinical specimens apparatus and method
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United States of America Patent
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Sep 6, 2005
Grant Date -
Jun 2, 2005
app pub date -
Dec 27, 2002
filing date -
Oct 11, 1995
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A method for the multiplexed diagnostic and genetic analysis of enzymes, DNA fragments, antibodies, and other biomolecules comprises the steps of constructing an appropriately labeled beadset, exposing the beadset to a clinical sample, and analyzing the combined sample/beadset by flow cytometry. Flow cytometric measurements are used to classify, in real-time, beads within an exposed beadset and textual explanations, based on the accumulated data obtained during real-time analysis, are generated for the user. The inventive technology enables the simultaneous, and automated, detection and interpretation of multiple biomolecules or DNA sequences in real-time while also reducing the cost of performing diagnostic and genetic assays.
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