System for electrophysiological measurements

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 6932893
APP PUB NO 20020063067A1
SERIAL NO

09967932

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Abstract

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The present invention relates to a high through-put system for determining and/or monitoring electrophysiological properties of ion channels of ion channel-containing membranes, typically lipid membrane-containing structures such as cells. In particular, the invention provides a substrate which provides means for automatically positioning cells at measuring sites using electroosmotic flow in canals formed on or in the substrate. The electroosmotic flow is generated and controlled by electroosmotic flow pumps integrated on the substrate or positioned in relation thereto. Thereby, cells can be positioned in favorable measurement configuration at a plurality of sites for performing testing and measurements. Also, the invention relates to a main electric circuit for performing testing and measurements on a plurality of cells in parallel.

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SOPHION BIOSCIENCE A/SBALLERUP

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bech, Morten Holte, DK 6 169
Dodgson, John Croydon, GB 18 317
Due, Jorgen Ølstykke, DK 7 136
Kutchinsky, Jonatan Frederiksberg C, DK 17 84
Nielsen, Bent Erling Lyngby, DK 1 44
Shaw, John West Drayton, GB 40 403
Taboryski, Rafael Lyngby, DK 10 89
Thomsen, Lars Aalborg Ø, DK 20 330

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