Conversion of liquid filled gelatin capsules into controlled release systems by multiple coatings
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United States of America Patent
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Aug 16, 2005
Grant Date -
Oct 24, 2002
app pub date -
Apr 4, 2002
filing date -
Dec 17, 1998
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A dosage form comprising a gelatin capsule formed with a composite wall and containing a liquid, active agent formulation where the wall comprises a barrier layer formed over the external surface of the gelatin capsule, an expandable layer formed over the barrier layer and a semipermeable layer formed over the expandable layer is described. The dosage forms and methods provide for the conversion of standard gelatin, liquid formulation capsules into controlled, release dosage forms that permit the controlled release of the active agent into the environment of use over time.
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