DNA Molecules
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United States of America Patent
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Jul 26, 2005
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N/A
app pub date -
Mar 12, 1996
filing date -
Mar 13, 1995
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Abstract
The present invention provides novel nucleic acid molecules coding for sigma subunits of Mycobacterium tuberculosis RNA polymerase. It also relates to polypeptides, referred to as SigA and SigB, encoded by such nucleic acid molecules, as well as to vectors and host cells transformed with the said nucleic acid molecules. The invention further provides screening assays for compounds which inhibit the interaction between a sigma subunit and a core RNA polymerase.
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