Process for labeling a ribonucleic acid
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United States of America Patent
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Jul 26, 2005
Grant Date -
Dec 12, 2002
app pub date -
Mar 20, 2002
filing date -
Jun 17, 1998
priority date (Note) -
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Abstract
The present invention relates to a process for labeling a synthetic or natural ribonucleic acid (RNA). It also relates to RNA fragments, which have been labeled by fragmenting the RNA to free a terminal phosphate of each fragment for further reaction, and labeling each fragment at the freed terminal phosphate which is located at the 3′ end and/or the 5′ end of each fragment of the RNA, and to the use of such RNA fragments, for example, in the field of medical diagnosis.
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