Isolation of the lamin γ2 gene in horses and its use in diagnostic junctional epidermolysis bullosa
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United States of America Patent
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Jul 12, 2005
Grant Date -
Jul 31, 2003
app pub date -
Jan 24, 2002
filing date -
Jan 24, 2002
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Abstract
The laminin γ2 subunit of equine laminin-5 gene has been cloned and the nucleic acid and corresponding protein amino acid sequence is provided. A method of diagnosing junctional epidermolysis bullosa in horses is also provided based on the determination that a mutation in the laminin γ2 gene in which a cytosine is inserted at position 1368 is associated with the disease.
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