Ret-independent signaling pathway for GDNF
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United States of America Patent
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Jun 14, 2005
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N/A
app pub date -
Oct 1, 1999
filing date -
Oct 1, 1998
priority date (Note) -
Expired
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Abstract
Methods for screening for agonists and antagonists of GPI-anchored independent intracellular signaling resulting in [Ca2+]i elevation, ERK1, ERK2 and CREB phosphorylation, and Src family kinase activation are described, as well as methods for treatment involving administration of agonists/antagonists of such signaling.
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