Isoquinuclidine derivative process for producing the same, and medicinal composition containing the same

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United States of America Patent

PATENT NO 6903111
APP PUB NO 20040067911A1
SERIAL NO

10467719

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Abstract

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An isoquinuclidine derivative represented by the following general formula (I): (I) [wherein A1 is methylene or carbonyl]: R1 is hydrogen or methyl: R2 is —(CH2)n-A2-Ph (n is an integer of 0 to 3 and A2 is a single bond or —O—): and R3 is —COOH, —COOR4, —COSR4 (R4 is lower alkyl, unsubstituted phenyl, or phenyl substituted by a lower alkyl, lower alkoxy, hydroxyl, methoxycarbonyl, ethoxycarbonyl, or trifluoromethanesulfonamide group or by a halogen atom), etc.] or a pharmaceutically acceptable salt of the compound. Also provided is an oral remedy for diabetes, which contains the compound and has hypoglycemic activity. ##STR1##

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Patent Owner(s)

Patent OwnerAddress
KOTOBUKI PHARMACEUTICAL CO LTDHANISHINA-GUN NAGANO 389-0697

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kobayashi, Yoshinori Nagano, JP 175 2883
Noda, Atsushi Nagano, JP 80 1848
Tomiyama, Hiroshi Nagano, JP 38 811

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