Cartilage/bone inducing materials for reparation
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United States of America Patent
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Jun 7, 2005
Grant Date -
Nov 14, 2002
app pub date -
Nov 14, 1996
filing date -
Nov 17, 1995
priority date (Note) -
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Abstract
A cartrilage and bone morphogenetic repairing composition comprising a collagen-free aqueous solution of a polyoxyethylene-polyoxypropylene and an effective amount of a bone morphogenetic protein, the molecular weight of polyoxypropylene as a constituent of said polyoxyethylene-polyoxypropylene molecular is 900 to 4,000 in a unit of Dalton (D) and the ethylene oxide content is 5 to 90% by weight of the polyoxyethylene-propoxypropylene molecule whereby the solution is liquid at 1 to 30° C. and gelatinizes at about 37° C. and a method of using the same.
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