Modified cytokine receptor protein
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United States of America Patent
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May 10, 2005
Grant Date -
Jan 9, 2003
app pub date -
Feb 17, 1998
filing date -
Feb 18, 1997
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Expired
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Abstract
A modified extracellular domain of a cytokine receptor is capable of being crystallized without being complexed to a ligand molecule. The receptor preferably is a homo- or heterodemeric receptor having at least one molecule segment which contributes to a disorder structure deleted. A preferred receptor is human growth hormone receptor (hGHR).
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