Inhibitors of proteasomal activity for stimulating hair growth
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United States of America Patent
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Apr 26, 2005
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N/A
app pub date -
Apr 25, 2000
filing date -
Jul 10, 1998
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Abstract
Compounds that inhibit the activity of NF-.kappa.B or inhibit the activity of the proteasome or both promote bone formation and hair growth and are thus useful in treating osteoporosis, bone fracture or deficiency, primary or secondary hyperparathyrdidism, periodontal disease or defect, metastatic bone disease, osteolytic bone disease, post-plastic surgery, post-prosthetic joint surgery, and post-dental implantation; they also stimulate the production of hair follicles and are thus useful in stimulating hair growth, including hair density, in subject where this is desirable.
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