Method and apparatus for examining fluids of biological origin

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United States of America Patent

PATENT NO 6882425
SERIAL NO

10018080

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Abstract

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A quality test of fluids of biological origin can be performed optically with applying a suitable evaluation method. In case of two components to be determined in a such fluid, an extinction spectrum is approximated in a first wavelength range by a combination of a merely theoretical curve and the spectrum of the pure first substance in a first wavelength range, and this evaluation is repeated in a second wavelength range this time by approximating the measured spectrum (62) by a combination of a hypothetical curve, the spectrum (64) of the first component with the already determined concentration, and the spectrum (65) of the pure second component. Furthermore, it is feasible to subtract the first and second spectrum and analyze the so obtained differential spectrum (66) in view of anomalies. The hypothetical curves are preferably straight lines which are defined by slope and ordinate section. In the praxis of the quality test of blood, bilirubin and hemoglobin may be quantitatively be determined, whilst the background together with the lipid component can be qualitatively examined by means of the differential spectrum.

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Patent Owner(s)

Patent OwnerAddress
ROCHE DIAGNOSTICS CORPORATION9115 HAGUE ROAD INDIANAPOLIS IN 46250

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Elsenhans, Olivier Sins, CH 14 107
Sarofim, Emad Hagendorn, CH 61 1273
Schnell, Urban Georg Muntschemier, CH 2 8

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