Meiotic spindle imaging in oocytes and uses therefor in in vitro fertilization
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United States of America Patent
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Apr 12, 2005
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N/A
app pub date -
Jun 25, 2001
filing date -
Jun 23, 2000
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Abstract
The developmental potential of a mammalian oocyte for successful implantation is evaluated by producing a plurality of intensity images of the oocyte using polarized light optics, and calculating a retardance image with a sensitivity of 3 nm or less. The presence, location and morphological characteristics of a meiotic spindle in the oocyte can then be determined based on the spindle structure in the retardance image, and the developmental potential of the oocyte can be evaluated.
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