Method for producing cell-fushion type morbillivirus mutants
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United States of America Patent
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Apr 5, 2005
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N/A
app pub date -
Oct 28, 2002
filing date -
Nov 19, 1999
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Abstract
It was found that a mutation of an amino acid at a specific position in the F protein of a morbillivirus induces a reduction in the cell-fusion ability. By introducing this mutation, a virus having a reduced cell-fusion ability can be produced. Thus, attenuated viruses useful in the preparation of vaccines can be easily produced.
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