Method and apparatus for impurity detection
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United States of America Patent
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Mar 8, 2005
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N/A
app pub date -
Jul 14, 2003
filing date -
Apr 27, 2000
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Abstract
A method and apparatus is provided for detecting an impurity in a sample where an index can be calculated to assess purity in the presence of n major components with signal averaging or noise-filtering automatically built-in. The method and apparatus can be applied to liquid chromatography impurity detection using UV-VIS spectrophotometry based on robust matrix algebra representing the entire spectral space generated by the sample.
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