Fungicidal echinocandin derivatives and their preparation
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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Mar 8, 2005
Grant Date -
Jan 22, 2004
app pub date -
Dec 3, 2002
filing date -
Feb 15, 2000
priority date (Note) -
Expired
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Abstract
The invention concerns compounds of general formula (I) wherein: R.sub.1 represents a hydrogen atom, a hydroxy radical, Ob or Ncd; A represents an oxygen atom, a CH.sub.2 radical or a NH radical; B represents the radical of a steroid; R.sub.3 represents a hydrogen atom, a methyl or hydroxyl radical; R.sub.4 represents a hydrogen atom or a hydroxyl radical; T represents a hydrogen atom, a methyl radical, a CH.sub.1 CONH.sub.2, CH.sub.2 C.ident.N radical, a (CH.sub.2).sub.2 NH.sub.2 or (CH.sub.2)2Nalk.sup.+ X.sup.- radical; X being a halogen atom and alc an alkyl radical; Y represents a hydrogen atom, a hydroxyl radical or a halogen atom or a OSO.sub.3 H radical; W represents a hydrogen atom or a OH radical; Z represents a hydrogen atom or a methyl radical. The compounds of formula (I) exhibit antifungal properties. ##STR1##
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