Production of heterologous polypeptides from freshwater caulobacter

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United States of America Patent

PATENT NO 6861245
SERIAL NO

09913414

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Abstract

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A method is provided for screening Caulobacter suitable for use as host organisms for secretion of heterologous polypeptides. Such Caulobacter have a transport protein homologous to one of the type I transport proteins known in C. crescentus. DNA constructs are also provided which code for a chimeric protein of which the C-terminus is a secretion signal of a Caulobacter surface layer protein, other than from C. crescentus. Bacterial cells containing, or which express such DNA constructs and which may secrete the resulting protein, are also provided.

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Patent Owner(s)

Patent OwnerAddress
SMIT JOHN KENNETH DR9960 SEACASTLE DRIVE RICHMOND BC V7A4R8

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Inventor Name Address # of filed Patents Total Citations
Smit, John Richmond, CA 12 47

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