Siastatin B derivatives having a glycosidase inhibitory activity and processes for producing the same

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United States of America Patent

PATENT NO 6852735
SERIAL NO

09868780

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Abstract

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A compound of the formula (I): ##STR1## and a compound of the formula (V): ##STR2## as well as a compound of the formula (X): ##STR3## which are each a novel siastatin B derivative having a potent inhibitory activity against a glycosidase, are now synthesized by new processes. The compound of the formula (I), the compound of the formula (V) and the compound of the formula (X) have a potent enzyme-inhibitory activity to a glycosidase, which is particularly N-acetyl-galactosaminidase, galactosidase, glucosidase and mannosidase.

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Patent Owner(s)

Patent OwnerAddress
MEIJI SEIKA KAISHA LTDTOKYO JAPAN
ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI14-23 KAMI OHSAKI 3-CHOME SHINAGAWA-KU TOKYO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Nishimura, Yoshio Komae, JP 55 432
Shitara, Eiki Yokohama, JP 19 95
Takeuchi, Tomio Tokyo, JP 164 840

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