Anti-P53 single-chain antibody fragments and their uses

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United States of America Patent

PATENT NO 6852509
SERIAL NO

09297181

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention concerns single-chain antibodies directed against the p53 protein, capable of being expressed in tumoral cells, capable of restoring a DNA binding in vitro and a transcription activator function in vivo. The invention also concerns nucleic acids coding for these molecules, the vectors containing them and their uses.

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Patent Owner(s)

Patent OwnerAddress
INSTITUT NATIONAL DE LA RECHERCHE MEDICALE101 RUE DE TOLBIAC PARIS 75013

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bracco, Laurent 30 rue Deparcieux, 75014 Paris, FR 20 90
Caron, De Fromentel Claude 22 route de Collonges, Saint Cyr au Mont d'Or, 69450, FR 1 2
Debussche, Laurent 112, Avenue Jean Jaures, 91200 Athis Mons, FR 16 45

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