Escape mutants of Newcastle disease virus as marker vaccines
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United States of America Patent
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Dec 21, 2004
Grant Date -
Jul 8, 2004
app pub date -
Dec 2, 2003
filing date -
Dec 6, 2002
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Abstract
A vaccine against Newcastle Disease contains one or more mutant immunogens of the NDW strain. The mutant immunogen lacks the antigenic binding site on the F glycoprotein which is recognized by the monoclonal antibody mAb 54. Reagent kits and assay methods help to distinguish vaccinated members of a poultry flock from those that may have been infected with wild-type Newcastle Disease virus.
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