Methods for isoelectric particle separation

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United States of America Patent

PATENT NO 6833061
SERIAL NO

09147951

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Abstract

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In order to isoelectrically separate particles with a pH-dependent net charge, the particles are exposed in a guiding liquid to electric field forces. The pH value of the guiding liquid is set in such a way that at least one predetermined type of particle is separated from the remaining particles and migrates to a fixing collecting means under the effect of the electric field forces. The collecting means is for example a porous hollow fiber delimited by electrodes which generate the electric field forces and crossed by the guiding liquid together with the sample to be separated. The particles whose isoelectric point matches the pH value of the guiding liquid run unimpeded through the fibers, whereas the remaining particles are pressed against the inner wall of the fiber and are prevented from being carried away with the liquid flow.

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Patent Owner(s)

Patent OwnerAddress
EVOTEC TECHNOLOGIES GMBH40225 DÜSSELDORF

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ehwald, Rudolf Berlin, DE 18 401
Fuhr, Gunter Berlin, DE 37 991
Korlach, Jonas Berlin, DE 134 10368

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