Preparation of n-protected-3-pyrrolidine-lactam substituted phosphonium salts
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United States of America Patent
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Dec 7, 2004
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app pub date -
Feb 14, 2003
filing date -
Aug 14, 2000
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Expired
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Abstract
A new process is disclosed for the preparation of bipyrrolidinyl compounds of formula I ##STR1## wherein * signifies an asymmetric center with an (R) or (S) configuration and X represents chlorine, bromine or iodine. The compounds of formula I are important building blocks for the production of useful products in the chemical and in the pharmaceutical industry. In particular they are useful for the production of antibacterial substances such as vinylpyrrolidinone-cephalosporin derivatives.
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