Therapeutic and diagnostic methods and compositions based on Jagged/Notch proteins and nucleic acids
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United States of America Patent
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Nov 30, 2004
Grant Date -
May 1, 2003
app pub date -
Aug 6, 2002
filing date -
May 31, 1996
priority date (Note) -
Expired
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Abstract
This invention relates to therapeutic and diagnostic methods and compositions based on Jagged/Notch proteins and nucleic acids, and on the role of their signaling pathway in endothelial cell migration and/or differentiation. In addition, this invention provides a substantially purified Jagged protein, as well as a substantially purified nucleic acid molecule or segment thereof encoding Jagged protein, or a functionally equivalent derivative, or allelic or species variant thereof.
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