Substituted 5-benzyl-2,4-diaminopyrimidines

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United States of America Patent

PATENT NO 6821980
SERIAL NO

10129461

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to substituted 5-benzyl-2,4-diaminopyrimidines of general formula (A) ##STR1## wherein R.sup.1 is C2-C3 alkyl an R.sup.2 is heterocyclyl, phenyl or naphthyl, bonded by one of its C-atoms and R.sup.3 is C2-C6 alkyl, alkenyl, cycloalkyl, cycloalkylalkyl, heterocyclylalkyl, alkylsulfonyl, cycloalkylsulfonyl, cycloalkylalkylsulfamoyl, heterocyclysylfonyl, heterocyclylalkylsulfonyl or dialkylsulfamoyl; wherein alkyl, cycloalkyl and alyenyl can carry up to 6 carbon atoms alone or in compositions and can carry up to 6 ring members heterocyclically, alone, or in compositions and the groups R.sup.2 and R.sup.3 can be substituted; and to acid addition salts of compounds. The invention also relates to a method for producing the above 5-benzyl-2,4-diaminopyrimidines, to the intermediate. products that are produced, to corresponding medicaments and to the use of 5-benzyl-2,4-diaminopyrimidines as medicinal preparations. The products have antibiotic properties and are useful for combating or preventing infectious diseases.

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Patent Owner(s)

Patent OwnerAddress
BASILEA PHARMACEUTICA AG4058 BASEL

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Guerry, Philippe Binningen, CH 20 124
Mohr, Peter Basel, CH 115 1301
Mueller, Werner Augarten, CH 99 881
Muller, Marc St. Louis, FR 36 399
Pflieger, Philippe Schwoben, FR 70 171

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