Selective MMP inhibitors having reduced side-effects
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United States of America Patent
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Nov 16, 2004
Issued Date -
N/A
app pub date -
May 21, 2001
filing date -
Mar 3, 1997
priority date (Note) -
Expired
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Abstract
The subject invention pertains to matrix metalloproteinase (MMP) inhibitors that exhibit an IC.sub.50 of below 10.sup.-4 M against MMP and have substantially no activity against non-MMP metalloproteinase-related events. The MMP inhibitors of the invention have reduced side-effects, especially with respect to joint pain.
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