Process for producing L-epi-2-inosose and novel process for producing epi-inositol

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United States of America Patent

PATENT NO 6818430
SERIAL NO

09980453

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Abstract

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Provided are novel processes for the efficient production of L-epi-2-inosose and epi-inositol which are useful either as various medicines or intermediates for the syntheses of various medicines. In the processes, there is used inexpensive myo-inositol as a starting compound. That is, there is now developed a new process which comprises reacting myo-inositol with a gram-negative bacterium capable of converting myo-inositol into L-epi-2-inosose, and thereby producing L-epi-2-inosose by conversion of myo-inositol into L-epi-2-inosose. Further, a novel process is provided, which comprises reacting the so produced L-epi-2-inosose with a reducing agent made of an alkali metal boron hydride or any other alkali metal hydride in an aqueous reaction medium, to produce epi-inositol and myo-inositol, and then isolating epi-inositol from the resulting reaction product composed of the epi-inositol and myo-inositol.

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Patent Owner(s)

Patent OwnerAddress
ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI14-23 KAMI OHSAKI 3-CHOME SHINAGAWA-KU TOKYO
HOKKO CHEMICAL INDUSTRY CO LTD5-4 NIHONBASHI HON-CHO 1-CHOME CHUO-KU TOKYO 103-8341

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kanbe, Kenji Yokohama, JP 7 22
Kita, Yuichi Atsugi, JP 53 263
Mori, Tetsuya Atsugi, JP 83 916
Takahashi, Atsushi Kawasaki, JP 443 3708
Takeuchi, Tomio Tokyo, JP 164 840
Tamamura, Tsuyoshi Yamato, JP 2 2

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