Methods for encapsulating plasmids in lipid bilayers

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United States of America Patent

PATENT NO 6815432
APP PUB NO 20030181410A1
SERIAL NO

10374673

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Abstract

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Plasmid-lipid particles which are useful for transfection of cells in vitro or in vivo are described. The particles can be formed using either detergent dialysis methods or methods which utilize organic solvents. The particles are typically 65-85 nm, fully encapsulate the plasmid and are serum-stable.

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Patent Owner(s)

Patent OwnerAddress
THE UNIVERSITY OF BRITISH COLUMBIAVANCOUVER BRITISH COLUMBIA V6T 1Z3
TEKMIRA PHARMACEUTICALS CORPORATION8900 GLENLYON PARKWAY BURNABY V5J 5J8

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bally, Marcel B Bowen Island, CA 38 4823
Cullis, Pieter R Vancouver, CA 82 6269
Hope, Michael Vancouver, CA 14 2066
Wheeler, Jeffery J Richmond, CA 15 1987

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