Ultrasound imaging with contrast agent targeted to microvasculature and a vasodilator drug
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United States of America Patent
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Nov 2, 2004
Grant Date -
N/A
app pub date -
Apr 20, 2000
filing date -
Oct 21, 1997
priority date (Note) -
Expired
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Abstract
A combined preparation comprising: i) an ultrasound contrast agent capable of accumulation in tissue microvasculature; and ii) a pharamacologically effective amount of a vasodilator drug may be used in perfusion imaging, especially of the myocardium. The contrast agent accumulates in tissue in concentrations related to the regional rate of tissue perfusion, and the vasodilator drug enhances distinction between normally perfused and underperfused tissue.
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